Former Southampton boss Dave Merrington says the team must forget about Newcastle’s predicament and focus on themselves this Saturday.
Saints host a Magpies team that is currently 19th in the Barclays Premier League and embroiled in the thick of the relegation battle, with six points separating them from safety.
While their situation might be perilous, Ronald Koeman’s side also have a significant need for the points, as they look to finish the campaign strongly and secure European qualification.
"It's a game where I think they've got to forget about Newcastle's predicament," Merrington said. "They're going to be scrapping and fighting for their lives. I think Saints have just got to be totally focused on getting the three points."
Despite last Sunday's 1-0 defeat at leaders Leicester, which ended a three-match unbeaten run, Merrington believes there is some confidence to be taken from the trip to King Power Stadium.
"It was a difficult game for Leicester," he said. "Leicester have taken the three points, but it could quite easily have been different. But on the back of it I think it should give them confidence, the manner of performance they turned in.
"But I think they've got to concentrate now on taking one game at a time. That first game now at home is Newcastle and it's one you cannot afford to pick up only one point from.
"I think every game from now until the end of the season they have to be at maximum. I think they've got to take each game separately, but they've got to be totally focused that nobody from the squad can be less than at maximum. That's so important if they're going to get into the top six, or push the others round about them."