Jack Stephens, Jordan Turnbull and Sam Gallagher have all been in action with their temporary clubs over the last week.
Gallagher played the full 90 minutes as MK Dons suffered a 2-0 defeat at home to Birmingham City in the Championship on Saturday.
Gallagher returned to the side following three substitute appearances against Birmingham, but was unable to prevent a second home defeat of the season.
Stephen Gleeson and Jacques Maghoma scored second-half goals for the visitors as Karl Robinson’s side suffered defeat.
The striker played an hour in the Capital One Cup last Tuesday as the Dons beat Cardiff City.
Gallagher came on in the 61st minute with the score at 1-0, and helped his side turn the game around after extra time.
Carl Baker’s goal took the game to extra time before Josh Murphy won the game in the 108th minute to second up a third-round clash with Saints.
Turnbull was also on the losing side at the weekend as Swindon Town lost 2-0 at home to Sheffield United.
Nigel Adkins’s side won the game thanks to goals from Neill Collins and former Saints man Billy Sharp in the second half, with Turnbull playing 90 minutes.
Stephens was not involved on Saturday as Middlesbrough picked up an important win at Sheffield Wednesday in the Championship.
Goals from Adam Reach, Diego Fabbrini and Christian Stuani sealed a 3-1 success for Aitor Karanka’s side at Hillsborough.
Stephens did play 45 minutes in midweek as Boro beat League 1 side Burton Albion in the Capital One Cup. Stuani scored twice, with the winner coming in extra time, to send them into the next round.